Tirzepatide is a novel medication designed for the treatment of type 2 diabetes and for weight management in individuals with obesity. It represents a new class of therapeutic agents by simultaneously activating two different receptors: the GLP-1 (glucagon-like peptide-1) receptor and the GIP (glucose-dependent insulinotropic polypeptide) receptor. This dual mechanism of action is innovative because it not only enhances the body's ability to lower blood sugar levels but also supports weight loss, making it a promising treatment option for individuals managing both type 2 diabetes and obesity.

Tirzepatide works by mimicking the effects of natural hormones in the body that help regulate blood sugar levels. By activating the GLP-1 receptor, it increases insulin release in response to high blood sugar levels, decreases glucagon production (which otherwise raises blood sugar levels), and slows gastric emptying to help control appetite and food intake. The activation of the GIP receptor further enhances insulin release and plays a role in managing energy balance and fat storage.

The medication is administered through subcutaneous injection, typically once a week, which may offer convenience and improve adherence for patients compared to treatments requiring more frequent dosing.

Clinical trials have demonstrated tirzepatide's effectiveness in lowering blood glucose levels and promoting significant weight loss, making it an important addition to the treatment options available for type 2 diabetes and obesity. However, as with any medication, it is essential to consult with a healthcare provider to discuss the potential benefits and risks, considering an individual's specific health profile and treatment goals.

Administration

• Form: Tirzepatide is available as a subcutaneous injection.
• Frequency: It is typically injected once a week, and you can choose any day of the week that works best for you, but try to stick to the same day each week.
• Injection Sites: The injection can be made into the abdomen, thigh, or upper arm. It’s recommended to rotate the injection sites to avoid skin problems.